Reported Resistance Case(s)

Species: spodoptera frugiperda

Order	Family	Common Name(s)	Group	Host
lepidoptera	noctuidae	fall armyworm	AG	cotton, grains, grasses, sugarcane

Active Ingredient: Spinetoram

MOA: Nicotinic Acetylcholine receptor agonists (allosteric), Spinosyns
Group: SPIN	CAS #: 187166401	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G23580	2025	Field Evolved Resistance	Pakistan-- Punjab-- Faisalab	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23573	2025	Field Evolved Resistance	Pakistan-- Punjab-- Jhang	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23566	2025	Field Evolved Resistance	Pakistan-- Punjab-- Sialkot	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23560	2025	Field Evolved Resistance	Pakistan-- Punjab-- Mian Channu	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23553	2025	Field Evolved Resistance	Pakistan-- Punjab-- Lahore	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23546	2025	Field Evolved Resistance	Pakistan-- Punjab-- Pattoki	Khan, H. A. A., and Ali, A. (2025). First report of field-evolved resistance to insecticides in Spodoptera frugiperda (Lepidoptera: Noctuidae) from Punjab, Pakistan. Plos One.
G23061	2024	Lab selected after field-evolved resistance**	Brazil-- Bahia-- Sao Desiderio	Rubens H. Kanno, Antonio R.B. Nascimento, Carolina P. Monteiro, Fernando S.A. Amaral, Kumar S. Singh, Bartlomiej J. Troczka, Chris Bass, Fernando L. Cônsoli, Celso Omoto,. (2024). Bulk segregant mapping and transcriptome analyses reveal the molecular mechanisms of spinetoram resistance in Spodoptera frugiperda. Pesticide Biochemistry and Physiology, 202.
G22160	2023	Lab selected after field-evolved resistance**	Brazil-- São Desidério	Kanno, Rubens & Guidolin, Aline & Padovez, Fernando & Rodrigues, Juliana & Omoto, Celso. (2023). Fitness costs associated with spinetoram resistance in Spodoptera frugiperda is driven by host plants.. Journal of Pest Science. 1-11.
G22001	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G22000	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21999	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G20472	2020	Lab selected*	Brazil-- Barreiras-- Bahia	Lira, E.C., Bolzan, A., Nascimento, A.R., Amaral, F.S., Kanno, R.H., Kaiser, I.S. and Omoto, C. (2020). Resistance of Spodoptera frugiperda (Lepidoptera: Noctuidae) to spinetoram: inheritance and cross�resistance to spinosad. . Pest Management Science, 76 2674-2680.
G20033	2018	Field Evolved Resistance	Puerto Rico-- Ponce	Gutiérrez-Moreno, R., Mota-Sanchez, D., Blanco, C. A., Whalon, M. E., Terán-Santofimio, H., Rodriguez-Maciel, J. C., and DiFonzo, C. (2018). Field-evolved resistance of the fall armyworm (Lepidoptera: Noctuidae) to synthetic insecticides in Puerto Rico and Mexico. Journal of Economic Entomology.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.