Reported Resistance Case(s)

Species: drosophila melanogaster

Order	Family	Common Name(s)	Group	Host
diptera	drosophilidae	common fruit fly	AG

Active Ingredient: flubendiamide

MOA: Ryanodine receptor modulators, Diamides
Group: DIA	CAS #: 272451	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G21214	2021	Lab selected*	China	Huang JM, Sun H, He LF, Liu C, Ge WC, Ni H, Gao CF and Wu SF. (2021). Double ryanodine receptor mutations confer higher diamide resistance in rice stem borer, Chilo suppressalis.. Pest Management Science, 77 4971-4979.
G19823	2017	Lab selected*	USA-- Indiana	Douris, V., Papapostolou, K. M., Ilias, A., Roditakis, E., Kounadi, S., Riga, M., Nauen, R. and Vontas, J. (2017). Investigation of the contribution of RyR target-site mutations in diamide resistance by CRISPR/Cas9 genome modification in Drosophila. Insect Biochemistry and Molecular Biology, 87 127-135.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.