Reported Resistance Case(s)

Species: nilaparvata lugens

Order	Family	Common Name(s)	Group	Host
homoptera	delphacidae	brown planthopper	AG	rice

Active Ingredient: nitenpyram

MOA: Nicotinic Acetylcholine receptor agonists / antagonists, Neonicotinoids
Group: NICO	CAS #: 0	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G22851	2024	Lab selected after field-evolved resistance**	Philippines-- Nueva Ecija	Zhang, H., Lin, X., Yang, B., Zhang, L., & Liu, Z. (2024). Two Point Mutations in CYP4CE1 Promoter Contributed to the Differential Regulation of CYP4CE1 Expression by FoxO between Susceptible and Nitenpyram-Resistant Nilaparvata lugens. Journal of agricultural and food chemistry, 72.
G22852	2024	Lab selected after field-evolved resistance**	Philippines-- Nueva Ecija	Zhang, H., Lin, X., Yang, B., Zhang, L., & Liu, Z. (2024). Two Point Mutations in CYP4CE1 Promoter Contributed to the Differential Regulation of CYP4CE1 Expression by FoxO between Susceptible and Nitenpyram-Resistant Nilaparvata lugens. Journal of agricultural and food chemistry, 72.
G22854	2024	Lab selected after field-evolved resistance**	Philippines-- Nueva Ecija	Zhang, H., Lin, X., Yang, B., Zhang, L., & Liu, Z. (2024). Two Point Mutations in CYP4CE1 Promoter Contributed to the Differential Regulation of CYP4CE1 Expression by FoxO between Susceptible and Nitenpyram-Resistant Nilaparvata lugens. Journal of agricultural and food chemistry, 72.
G22857	2024	Lab selected after field-evolved resistance**	Philippines-- Nueva Ecija	Zhang, H., Lin, X., Yang, B., Zhang, L., & Liu, Z. (2024). Two Point Mutations in CYP4CE1 Promoter Contributed to the Differential Regulation of CYP4CE1 Expression by FoxO between Susceptible and Nitenpyram-Resistant Nilaparvata lugens. Journal of agricultural and food chemistry, 72.
G22725	2023	Lab selected after field-evolved resistance**	China-- Hubei	He, Minrong; Zhao, Xueyi; Chen, Xingyu; Shi, Yiyan; Wu, Shuai; Xia, Fujin; Li, Rongyu; Li, Ming; Wan, Hu; Li, Jianhong; Liao, Xun. (2023). Overexpression of NADPH-cytochrome P450 reductase is associated with sulfoxaflor resistance and neonicotinoid cross-resistance in Nilaparvata lugens (Stal). Agricultural and biological sciences, 194.
G22726	2023	Lab selected after field-evolved resistance**	China-- Hubei	He, Minrong; Zhao, Xueyi; Chen, Xingyu; Shi, Yiyan; Wu, Shuai; Xia, Fujin; Li, Rongyu; Li, Ming; Wan, Hu; Li, Jianhong; Liao, Xun. (2023). Overexpression of NADPH-cytochrome P450 reductase is associated with sulfoxaflor resistance and neonicotinoid cross-resistance in Nilaparvata lugens (Stal). Agricultural and biological sciences, 194.
G20971	2021	Field Evolved Resistance	China-- Hubei-- Jingmen	Liao, X., Xu, P. F.,Gong P. P., Wan, H., and Li, J. H. (2021). Current susceptibilities of brown planthopper Nilaparvata lugens to triflumezopyrim and other frequently used insecticides in China. Insect Science, 28 115-126.
G21143	2020	Lab selected after field-evolved resistance**	China-- Changsha-- Hunan	Mao, K., Ren, Z., Li, W., Cai1, T., Qin, X., Wan, H., Jin, B. R., He, S., and Li, J. (2020). Carboxylesterase genes in nitenpyram-resistant brown planthoppers, Nilaparvata lugens. Insect Science, 00 1-12.
G21144	2020	Lab selected after field-evolved resistance**	China-- Xinyang-- Henan	Mao, K., Ren, Z., Li, W., Cai1, T., Qin, X., Wan, H., Jin, B. R., He, S., and Li, J. (2020). Carboxylesterase genes in nitenpyram-resistant brown planthoppers, Nilaparvata lugens. Insect Science, 00 1-12.
G20043	2019	Lab selected after field-evolved resistance**	China	Mao, K., Zhang, X., Ali, E., Liao, X., Jin, R., Ren, Z., Wan, H., and Li, J. (2019). Characterization of nitenpyram resistance in Nilaparvata lugens (Stål). Pesticide Biochemistry and Physiology.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.