Reported Resistance Case(s)

Species: spodoptera frugiperda

Order	Family	Common Name(s)	Group	Host
lepidoptera	noctuidae	fall armyworm	AG	cotton, grains, grasses, sugarcane

Active Ingredient: indoxacarb

MOA: Voltage-dependent sodium channel blocker, Indoxacarb
Group: OXA	CAS #: 0	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G23204	2024	Field Evolved Resistance	Pakistan-- Punyab-- Multan	Zaidi, S. W. N., Saddiq, B., Afzal, M. B. S., Banazeer, A., Serrão, J. E., Farooq, U., & Baloch, M. A. Z. (2024). First report of resistance in Spodoptera frugiperda (Lepidoptera: Noctuidae) to lambda-cyhalothrin from Pakistan: baseline susceptibility, selection, occurrence of cross-resistance, realized heritability, and inheritance mode of resistance. Journal of Economic Entomology.
G21978	2022	Field Evolved Resistance	China-- Shishou	Guo, Z., Guo, Z., Gao, J., Huang, G., Wan, H., He, S., Xie, Y., Li, J., & Ma, K. (2022). Detection of insecticide susceptibility and target-site mutations in field populations of Spodoptera frugiperda (Lepidoptera: Noctuidae). International Journal of Pest Management.
G21988	2022	Lab selected after field-evolved resistance**	China-- Zhejiang	Hafeez, M., Li, X., Ullah, F., Zhang, Z., Zhang, J., Huang, J., Chen, L., Siddiqui, J. A., Ren, X., Zhou, S., Imran, M., Assiri, M. A., Zalucki, M. P., Lou, Y., & Lu, Y. (2022). Characterization of Indoxacarb Resistance in the Fall Armyworm: Selection, Inheritance, Cross-Resistance, Possible Biochemical Mechanisms, and Fitness Costs.. Biology.
G21996	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21997	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21998	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G22121	2022	Lab selected after field-evolved resistance**	China-- Zhejiang	Hafeez, M., Li, X., Ullah, F., Zhang, Z., Zhang, J., Huang, J., Fernández-Grandon, G. M., Khan, M. M., Siddiqui, J. A., Chen, L., Ren, X. Y., Zhou, S., Lou, Y., & Lu, Y. (2022). Down-Regulation of P450 Genes Enhances Susceptibility to Indoxacarb and Alters Physiology and Development of Fall Armyworm, Spodoptera frugipreda (Lepidoptera: Noctuidae).. Frontiers in physiology, 13.
G21991	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21992	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21993	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21994	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21995	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.
G21990	2023	Field Evolved Resistance	China	Chen, H. L., Hasnain, A., Cheng, Q. H., Xia, L. J., Cai, Y. H., Hu, R., Gong, C. W., Liu, X. M., Pu, J., Zhang, L., & Wang, X. G. (2023). Resistance monitoring and mechanism in the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) for chlorantraniliprole from Sichuan Province, China.. Frontiers in physiology.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.